2021 Mercedes-Benz E-Class Model Review with Prices, Photos, & Specs

2021 Mercedes-Benz E-Class Model Overview at Mercedes-Benz of Easton

Mercedes-Benz E-Class

Key Features

  • Starting at $54,250 MSRP*
  • Standard 2.0L inline-4 turbo engine (255 hp and 273 lb-ft of torque) or available 3.0L inline-6 turbo engine with EQ Boost (362 hp and 369 lb-ft of torque) with 9G-TRONIC 9-Speed automatic transmission
  • Mercedes-Benz User Experience (MBUX) with Voice Control multimedia system based on Artificial Intelligence
  • Available 4MATIC®
    all-wheel drive system
  • Smartphone Integration with Apple CarPlay® and Android Auto™
  • New-generation multifunction steering wheel with capacitive touch control buttons and galvanized shift paddles
  • Standard Blind Spot Assist, Active Brake Assist, and ATTENTION ASSIST®
  • 12.3-inch digital instrument cluster and touchscreen multimedia display

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About the Mercedes-Benz E-Class

For generations, the Mercedes-Benz E-Class Sedan has pioneered groundbreaking safety developments, introduced new luxury features, and inspired imitation from other automakers to emulate its iconic appeal. You’ll enjoy your choice of a standard 2.0-liter inline-4 turbocharged engine with 255 horsepower or an available 3.0-liter inline-6 turbocharged engine producing 362 horsepower. Tailored to suit every driving style, standard DYNAMIC SELECT lets you dial in its driving character with a few taps of a console-mounted paddle. Another hallmark of the E-Class legacy has been class-leading safety innovations and the 2021 model is no exception with several standard advanced safety features. Both drivers and passengers alike will experience unrivaled comfort from the luxurious interior of the E-Class. Every E-Class now comes equipped with the ingenious Mercedes-Benz User Experience (MBUX) with Voice Control multimedia system for a revolutionary way to access your favorite infotainment features.

What the Critics Say


Even with the focus on crossovers and SUVs, the E-class remains the heart and soul of Mercedes-Benz. It’s the company’s best-selling model series of all time, and the sedan variants receive a makeover for 2021 that includes redesigned exterior styling, new powertrains, and additional technology features.” — Car and Driver


We’ve praised the E-Class for its understated nature, and while the 2021 E-Class sedan has an added air of aggression, we like the new design and think it will look continue to look handsome well into the future. In front, the hood gets a pair of power domes, and new all-LED headlights complement a revised single-louver grille trimmed in chrome and gloss-black.” — Kelley Blue Book


What’s New for 2021

2021 is an exciting year for the Mercedes-Benz E-Class thanks to an assortment of enticing updates both inside and out. Changes to the exterior of the E-Class includes redesigned front and rear fascias, new headlights and taillights, a more prominently chiseled hood, and an all-new front grille. Inside the cabin, drivers will now enjoy an updated steering wheel with touch-capacitive controls, a larger 12.3-inch digital instrument cluster, and several new trim options. All models also come standard with the groundbreaking Mercedes-Benz User Experience (MBUX) infotainment system. In terms of performance, E 450 variants receive a new inline-6 turbocharged engine featuring a 48-volt mild-hybrid system. A new electrified E 350e plug-in hybrid variant is expected to launch later in the model year as well.

Mercedes-Benz E-Class Sedan Features

Mercedes-Benz E-Class Performance

Performance & Driver Assistance

You have numerous powertrain options to choose from with the Mercedes-Benz E-Class Sedan. Included as standard is a 2.0L inline-4 turbo engine which produces 255 horsepower and 273 lb-ft of torque. If you crave more power, the optional 3.0-liter inline-6 turbocharged engine boasts 362 horsepower along with 369 lb-ft of torque. A standard 9G-TRONIC 9-speed with shift paddles provides lightning-quick gear changes for instantaneous response. Available 4MATIC® all-wheel drive gives the E-Class stability and confidence in all weather conditions. The standard ECO-START®/Stop system helps maximize your fuel efficiency in stop-and-go traffic. DYNAMIC SELECT gives drivers the ability to fine-tune the driving character of the E-Class.

Mercedes-Benz E-Class Interior

Sophisticated Interior

While offering an elegantly athletic exterior design, the interior of the Mercedes-Benz E-Class Sedan is thoughtfully crafted to awaken your senses. An optional Air Balance cabin-air ionizer and aromatherapy system helps you relax with continuous fresh air inside the cabin. A panoramic 12.3-inch screen centralizes navigation, entertainment and countless comfort features using sharper graphics and more intuitive menus. Standard MBnavigation helps get you to your destination effortlessly with 3D maps, live traffic, searching via Yelp or HERE™, along with lane advice before turns. Expertly-sculpted seats are tailored to match the muscles in your body for superior comfort. Sweeping from door-to-door, exotic yet sustainable woods add a luxurious accent to the interior while 64-color LED ambiance helps set the mood.

Mercedes-Benz E-Class Safety

Innovative Safety

Safety has been a hallmark for the E-Class Sedan for decades and the 2021 model is no exception to this tradition. Featuring Car‑to‑X Communication, the E-Class is connected to a centralized information source that can send you in-car updates about driving conditions and potential hazards before you get to them. An industry first, PRESAFE® Sound can sense an impending collision, and emit a safe “pink noise” via the audio system to pre-trigger your ears’ natural defense against the loud noises of an accident. In the event of a side collision, PRESAFE® Impulse Side can rapidly inflate the front-seat bolster to move you further from an intrusion and help reduce the forces of impact. DRIVE PILOT takes intelligent cruise control to a new level with the ability to change lanes with just a touch of the turn-signal lever.


Trims & Specs

E 350 Sedan

E 350 Sedan

  • Starting at $54,250 MSRP*
  • 2.0L inline-4 turbo engine (255 hp and 273 lb-ft of torque)
  • Power tilt/sliding tinted glass sunroof
  • Mercedes-Benz User Experience (MBUX)
  • 12.3-inch digital instrument cluster
  • Power front seats with memory

E 350 4MATIC Sedan

E 350 4MATIC® Sedan

  • Starting at $56,750 MSRP*
  • 4MATIC® All-Wheel Drive with ESP® Dynamic Cornering Assist
  • All-LED exterior lighting
  • Car-to-X Communication
  • Electronic trunk closer
  • 64-color LED ambient lighting

E 450 4MATIC Sedan

E 450 4MATIC® Sedan

  • Starting at $62,000 MSRP*
  • 3.0L inline-6 turbo engine with EQ Boost (362 hp and 369 lb-ft of torque)
  • Optional Active multicontour front seats with massage
  • Adaptive braking technology with Crosswind Assist
  • Dual-zone automatic climate control
  • Available Burmester Surround Sound system

*Base MSRP excludes transportation and handling charges, destination charges, taxes, title, registration, preparation and documentary fees, tags, labor and installation charges, insurance, and optional equipment, products, packages and accessories. Actual vehicle price may vary by Dealer.

*Bluetooth is a registered mark Bluetooth SIG, Inc.